Crohn’s & Colitis Congress™

Sessions Speakers Exhibitors Floor Plan Buzz
Search

Sessions (143)

4 - CO-DELIVERY OF TNF-α SIRNA AND IL-22 VIA A NANOPARTICLE-IN-HYDROGEL SYSTEM EXERTS SYNERGISTIC THERAPEUTIC EFFECTS AGAINST ULCERATIVE COLITIS (Room Pinyon 3)

18 Jan 18
2:10 PM - 2:25 PM

Tracks: Clinical and Research Challenges, Lloyd Mayer, MD, Young IBD Investigators Workshop

Speaker(s): Emilie Viennois
Combination therapy is an emerging approach for treating ulcerative colitis (UC). During the development of UC, TNF-α acts as the major pro-i... More...

5 - LOSS OF ESTROGEN RECEPTOR BETA IN A SPONTANEOUS MODEL OF CROHN'S-LIKE ILEITIS REVEALS SEX-SPECIFIC FUNCTIONS OF ESTROGEN SIGNALING AMONG INTESTINAL REGULATORY T CELLS (Room Pinyon 3)

18 Jan 18
2:25 PM - 2:40 PM

Tracks: Clinical and Research Challenges, Lloyd Mayer, MD, Young IBD Investigators Workshop

Speaker(s): Wendy Goodman
Introduction Regulatory T cells (Tregs) isolated from IBD patients function properly ex vivo, but are unable to restrain chronic inflammation in si... More...

6 - MATRIX METALLOPROTEINASE MEDIATED CLEAVAGE OF SURFACE PD-L1 ON (MYO)FIBROBLAST CONTRIBUTES TO THE DYSREGULATION OF T-CELL RESPONSES IN CROHN’S DISEASE (Room Pinyon 3)

18 Jan 18
2:40 PM - 2:55 PM

Tracks: Clinical and Research Challenges, Lloyd Mayer, MD, Young IBD Investigators Workshop

Speaker(s): Jose Aguirre
Introduction: Increased Th1/Th17 immune response is a hallmark of Crohn’s Disease (CD) Immunopathogenesis. CD90+ (myo)fibroblasts (CMF) are a... More...

P001 - #IBD: A WORD ASSOCIATION ANALYSIS OF TWEETS ABOUT INFLAMMATORY BOWEL DISEASE (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges, Poster Session

Speaker(s): Marie Borum
Twitter, an online social networking service, is an important communication tool using messages (tweets) restricted to 140 characters. There is lim... More...

P002 - 2-ACCETYL-4-TETRAHYDROXYBUTYL IMIDAZOLE AMELIORATES DEXTRAN SULFATE SODIUM-INDUCED COLITIS VIA SUPPRESSION OF SPHINGOSINE-1-PHOSPHATE LYASE

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges, Poster Session

Speaker(s): Kazuhiko Shirakabe
Background: In the field of inflammatory bowel diseases (IBD), a variety of drug trials targeting on lymphocyte migration got hot during recent yea... More...

P003 - A COMPARISON OF THE MUCOSA-ASSOCIATED MICROBIAL COMMUNITY STRUCTURE BETWEEN INFLAMED AND NON-INFLAMED SITES IN PATIENTS WITH ULCERATIVE COLITIS

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges, Poster Session

Speaker(s): Atsushi Hirano
Background: The gut microbiota is suggested to play an important role in the pathogenesis of ulcerative colitis (UC). However, inter-individual and... More...

P004 - A DIET LOW IN RED AND PROCESSED MEATS DOES NOT REDUCE THE RATE OF CROHN’S DISEASE FLARES IN A RANDOMIZED CONTROLLED TRIAL: RESULTS OF THE FOOD AND CROHN’S DISEASE EXACERBATION STUDY (FACES)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges, Poster Session

Speaker(s): Lindsey Albenberg
Background: Diet may be an important factor in the natural history of Crohn’s disease (CD). We sought to determine whether exclusion of red a... More...

P005 - A MUCOSAL AND CHEMOKINE LIGAND FOR THE LYMPHOCYTE CHEMOATTRACTANT RECEPTOR GPR15 (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges, Poster Session

Speaker(s): Borja Ocon Moreno
Introduction and Background: Lymphocytes are key mediators of inflammation and IBD, including ulcerative colitis (UC). GPR15 is a chemoattractant r... More...

P006 - A NEW MODEL OF SPONTANEOUS INNATE IMMUNE MEDIATED COLITIS (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Anne-Marie Overstreet
Introduction: IBD is driven by excessive inflammation involving reciprocal interactions between innate and adaptive immune cells. To better underst... More...

P007 - QUALITATIVE STUDY OF THE EXPERIENCE OF ADULTS AND ADOLESCENTS WITH ULCERATIVE COLITIS (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Theresa Hunter
Background: Ulcerative colitis (UC), a chronic gastrointestinal disease, presents during one’s most productive years. The primary symptoms of... More...

P008 - A QUALITATIVE STUDY OF THE PATIENT EXPERIENCE OF PAIN AND PAIN-RELATED FUNCTIONAL IMPACTS SPECIFIC TO CROHN’S DISEASE (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): April Naegeli
Background: Crohn’s disease (CD) is a chronic inflammatory gastrointestinal (GI) disorder that may involve any site of the GI tract. CD is ch... More...

P009 - A RARE CASE OF A GASTRIC ABSCESS FISTULIZING TO THE DUODENUM IN CROHN’S DISEASE (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Marie Borum
Introduction: Clinically significant gastroduodenal involvement of Crohn’s disease (CD) is rare, affecting only 0.5-4% of CD patients. Gastri... More...

P010 - ADHERENCE TO INFLIXIMAB FOR INFLAMMATORY BOWEL DISEASE, A MULTICENTER RETROSPECTIVE REVIEW (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Shail Govani
Background: Non-adherence to Infliximab (IFX) is associated with an increased risk of anti-drug antibodies which can lead to loss or response. We p... More...

P011 - ADHERENT-INVASIVE ESCHERICHIA COLI UTILIZES SERINE CATABOLISM TO OUTCOMPETE ITS COMMENSAL COMPETITORS (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Sho Kitamoto
Backgrounds: Crohn's disease (CD) patients are often colonized by adherent-invasive Escherichia coli (AIEC). Although the colonization by AIEC ... More...

P012 - ANTI-TNF DRUG ANTIBODY LEVELS CORRELATE WITH POST-SURGICAL RECURRENCE IN CROHN’S DISEASE (CD) (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Gregory Pajot
Introduction: The prevention of the recurrence of Crohn's disease (CD) after ileo-cecal resection remains difficult. Background: Anti-tumor nec... More...

P013 - APOPTOTIC ENTEROPATHY INDUCED BY THALIDOMIDE IN A PATIENT WITH REFRACTORY UPPER AND COLONIC CROHNS’ DISEASE (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Jean Donet
Apoptotic bodies can be found to be marginally increased in untreated IBD. However, the presence of more than 6 apoptotic bodies per 10 contiguous ... More...

P014 - AVERAGE ANNUAL HEALTHCARE COSTS FOR PEDIATRIC AND ADULT PATIENTS WITH CROHN’S DISEASE OR ULCERATIVE COLITIS (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Robert Baldassano MD
Background: Crohn’s disease (CD) and ulcerative colitis (UC) are costly conditions that require life-long disease management. Both conditions... More...

P015 - BODY IMAGE DISSATISFACTION IN PEDIATRIC PATIENTS WITH INFLAMMATORY BOWEL DISEASES (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Jennifer Claytor
Background/Aims: Pediatric patients with inflammatory bowel diseases (IBD) are at increased risk for poor psychosocial outcomes, including body ima... More...

P016 - CASE SERIES: IMMUNOTHERAPY-INDUCED LYMPHOCYTIC COLITIS (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Kati Choi
Background: Immunotherapy enhances T cell’s action on tumor cells by inhibiting T cell inactivation. However, upregulation of T cells can lea... More...

P017 - CD47 REGULATES CD11B-DEPENDENT NEUTROPHIL TRANSEPITHELIAL MIGRATION DURING INTESTINAL INFLAMMATION (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Veronica Azcutia
Neutrophil (PMN) migration across the intestinal mucosa correlates with disease flares in individuals with IBD. Despite this correlation, molecular... More...

P018 - CLINICAL COURSE AND OUTCOMES OF INFLAMMATORY BOWEL DISEASE PATIENTS WHO UNDERWENT SOLID ORGAN TRANSPLANTATION IN KOREA (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Sung Wook Hwang
Background and Aims: According to the previous researches, there are variable results after solid organ transplantation (SOT) in inflammatory bowel... More...

P019 - CLINICAL EFFICACY OF ANTI-TNFA ANTIBODY TREATMENT IN PATIENTS WITH DEFINITE OR SUSPECTED INTESTINAL BEHCET DISEASE (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Keizo Zeze
Background: Although anti-TNFα antibody treatment has been used for definite or suspected intestinal Behcet disease (BD), the efficacy of the... More...

P020 - COLONIC INHIBITION OF PHOSPHATASE AND TENZIN HOMOLOG (PATEN) INCREASES COLITOGENIC BACTERIA, INDUCING COLITIS IN IL10 DEFICIENT MICE (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Sang Hoon Rhee
Background: Pten (phosphatase and tensin homolog) regulates microbe-induced immune responses in the gut. Thus, the intestinal deletion of Pten acce... More...

P021 - COMPLEMENTARY AND ALTERNATIVE MEDICINE IN INFLAMMATORY BOWEL DISEASE: WHERE'S THE DISCUSSION? (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Marie Borum
Background: The role of complementary and alternative medicine (CAM) have been used as adjunctive treatment in inflammatory bowel disease (IBD). It... More...

P022 - CROHN’S DISEASE AND ACUTE B LYMPHOBLASTIC LEUKEMIA – COINCIDENCE OR ASSOCIATION? (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Joana Castela
A 34-year-old male with Crohn’s disease (CD) (A2-L3-B3) and bad prognostic criteria at diagnosis, was treated with a “top down” s... More...

P023 - CROHN’S DISEASE AND ULCERATIVE COLITIS PATIENT PERSPECTIVES ON PARTICIPATION IN IBD CLINICAL TRIALS

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Peter Higgins
Background/Aims: Clinical trial recruitment is often the rate-limiting step in the development of new treatments reaching patients across all disea... More...

P024 - CROHN’S DISEASE MESSAGING ON TWITTER: WHO’S TALKING?

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Marie Borum
Twitter, a popular social networking service, enables users to interact with messages (tweets) limited to 140 characters. It is an increasingly pow... More...

P025 - CYSTATHIONINE-GAMMA-LYASE REGULATES MACROPHAGE INTERLEUKIN-10 (IL-10) PRODUCTION IN COLITIS (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Ketan Thanki
Background: Cystathionine-β-synthase (CBS) & cystathionine-γ-lyase (CSE), convert homocysteine into cysteine & produce H2S, an a... More...

P026 - DEVELOPMENT OF A PREFERENCE-WEIGHTED SYMPTOM SCALE FOR INFLAMMATORY BOWEL DISEASE (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Welmoed van Deen
Background: Practicing patient-centric care by incorporating patient preferences in IBD care is increasingly recognized to be important. However, e... More...

P027 - DIFFERENTIAL BINDING OF RBPJ AND CUX1 TO IBD CAUSAL SNP rs1887428 MODIFIES EXPRESSION OF JAK2 (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Christopher Cardinale
Background Recently, genetic variants conferring risk for IBD were fine-mapped to single variant resolution. Eight of these causal variants resulte... More...

P028 - DYSBIOSIS DRIVEN LUMINAL MALMETABOLISM INCREASES THE RISK OF C. DIFFICLILE INFECTION IN PATIENTS WITH ULCERATIVE COLITIS (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Hiroko Kitamoto
Backgrounds: Clostridium difficile infection (CDI) is recognized as a major clinical complication in patients with ulcerative colitis (UC). However... More...

P029 - ENDOCYTOSCOPIC FINDINGS PREDICT RELAPSE IN PATIENTS WITH ULCERATIVE COLITIS DURING LONG-TERM FOLLOW-UP NO LESS THAN 5 YEARS (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Yuichiro Ikebuchi
This study was conducted to explore the association of endocytoscopy (EC) findings with inflammatory activity and clinical course in ulcerative col... More...

P030 - ENPP1 EXPRESSION IN GUT MUCOSAL EPITHELIA INFLUENCES BARRIER FUNCTION VIA THE ADENOSINE PATHWAY (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Valerie Curtis
Previous work has established that extracellular adenosine signaling is protective in mucosal inflammation and promotes the resolution of ongoing i... More...

P031 - ENTERIC GLIA SHARE CHARACTERISTICS WITH ANTIGEN PRESENTING CELLS AND MAY ALTER SERUM CHEMOKINE LEVELS DURING NEUROINFLAMMATION (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Aaron Chow
The enteric nervous system (ENS) is intrinsic to the gastrointestinal (GI) tract and controls essential gut functions such as motility, blood flow ... More...

P032 - EPICERTIN ENHANCES INTESTINAL WOUND HEALING IN A MOUSE COLITIS MODEL AND HUMAN ULCERATIVE COLITIS COLON EXPLANTS (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Joshua Royal
Epicertin (EPT) is a new ulcerative colitis (UC) drug candidate derived from the nontoxic component of Vibrio cholerae cholera toxin. We have recen... More...

P033 - EPIGENETIC SILENCING OF SMAD7 CONTRIBUTES TO FIBROSIS IN STRICTURING CROHN’S DISEASE (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Chao Li
TGF-β1 is a central pro-fibrotic cytokine in stricturing Crohn’s disease. Its affects are normally inhibited by increased Smad7 expressi... More...

P034 - EXERCISE AS ADJUNCTIVE THERAPY IN INFLAMMATORY BOWEL DISEASE: AN EDUCATIONAL INTERVENTION CAN INCREASE PHYSICIAN AWARENESS (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Marie Borum
Exercise has been shown to be safe and have symptom reduction in patients with inflammatory bowel disease (IBD). However, there has been inconsiste... More...

P035 - EXOGENOUS ADMINISTRATION OF IRISIN DURING CHRONIC TNBS-INDUCED GUT INFLAMMATION REVERSES INFLAMMATION-INDUCED ALTERATIONS IN BONE TURNOVER (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Corinne Metzger
A comorbidity of inflammatory bowel disease (IBD) is inflammation-induced bone loss characterized by elevated bone resorption and decreased bone fo... More...

P036 - EXPLORING EARLY-RESPONSIVE PHARMACODYNAMIC BIOMARKERS IN PEDIATRIC INFLAMMATORY BOWEL DISEASE (IBD) (Room Poster Session)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Laurie Conklin
PURPOSE: The generation of high-quality pilot data that leads to “go/no-go decisions” regarding new or repurposed drugs is often proble... More...

P037 - FAECALIBACTERIUM IS INCREASED IN PATIENTS WITH CROHN’S DISEASE ON A LOW FIBER DIET (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Rajesh Shah
Background: Patients with fibrostenotic Crohn’s disease (CD) are commonly advised to avoid fiber during symptomatic episodes. Fiber intake mo... More...

P038 - FECAL MICROBIOTA TRANSPLANT (FMT) FOR IMMUNO-CHECKPOINT INHIBITOR-INDUCED COLITIS (ICI-C) IN A 50 YEAR OLD FEMALE WITH BLADDER CANCER (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Yinghong Wang
Background With the success of immunotherapy in oncology for the past 5-10 years, there are also associated toxicities, including colitis. The curr... More...

P039 - FECAL miRNAs SHAPE THE INTESTINAL MICROBIOTA (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Emilie Viennois
Inflammatory Bowel Diseases are associated with a disruption of the intestinal microbiota, called dysbiosis, determining event in the pathogenesis.... More...

P040 - FIBROBLAST GROWTH FACTOR-INDUCIBLE 14 (FN14) SIGNALING MEDIATES CROHN’S DISEASE (CD)-LIKE ILEITIS IN SAMP MICE (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Luca Di Martino
Background: TNF-like Weak Inducer of Apoptosis (TWEAK) and Fn14 are TNF superfamily members that were reported to be elevated in colonic samples of... More...

P041 - GLIAL CONNEXIN-43 REGULATES NEURO-IMMUNE INTERACTIONS IN THE MOUSE COLON (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Vladimir Grubisic
The enteric nervous system regulates gut reflexes. Our prior data show that enteric glia regulate the activity and survival of enteric neurons in h... More...

P042 - GREEN TEA EXTRACT, EGCG, INHIBITS DNMT-1, ER STRESS AND PREVENTS THE DEVELOPMENT OF INTESTINAL FIBROSIS IN MURINE CHRONIC TNBS-INDUCED COLITIS (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Chao Li
We reported that increased endoplasmic reticulum (ER) stress signaling in subepithelial myofibroblasts (SEMF) isolated from patients with stricturi... More...

P043 - HEALTHCARE SERVICE UTILIZATION AND COSTS OF CERTOLIZUMAB PEGOL VERSUS INFLIXIMAB TREATMENT IN PATIENTS WITH CROHN’S DISEASE (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Edward Lee
Background: Crohn’s disease treatment costs with certolizumab pegol (CZP) have been shown to be lower than infliximab (IFX), mainly due to lo... More...

P044 - HIF1A IS A SWITCH IN THE PRO- VS ANTI-INFLAMMATORY FOXP3 GENE CIRCUITRY NETWORKS IMPLICATED IN INFLAMMATORY BOWEL DISEASE. (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Olga Sarmento
Background: We have published data sets revealing the majority of FOXP3 gene targets in CD4+ lymphocytes isolated from Crohn’s lesions are si... More...

P045 - HIGH DIMENSIONAL IMMUNE PHENOTYPING AND TRANSCRIPTIONAL ANALYSES REVEAL ROBUST RECOVERY OF VIABLE HUMAN IMMUNE AND EPITHELIAL CELLS FROM CRYOPRESERVED INTESTINAL TISSUE (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Liza Konnikova
Background: Simultaneous analyses of peripheral and mucosal immune compartments can yield insight into the pathogenesis of mucosal-associated disea... More...

P046 - HISTOLOGIC MEASURES OF MUCOSAL HEALING CORRELATE WITH ENDOSCOPIC MEASURES OF DISEASE ACTIVITY AT BASELINE AND FOLLOWING INDUCTION THERAPY WITH THE JANUS KINASE 1 INHIBITOR FILGOTINIB IN ACTIVE CROHN’S DISEASE: RESULTS FROM FITZROY STUDY (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): William J. Sandborn
Background Filgotinib (fil), a selective JAK1 inhibitor, has shown efficacy in a randomized double-blind, placebo (pbo)-controlled phase 2 study in... More...

P047 - HISTOLOGICAL AND ENDOSCOPIC HEALING AFTER QBECO TREATMENT IN AN OPEN-LABEL PHASE 2 STUDY IN PATIENTS WITH ULCERATIVE COLITIS (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Jim Pankovich
Introduction: Current therapies for inflammatory bowel disease (IBD) are aimed at immune suppression. These have not prevented disease progression ... More...

P048 - HISTORY OF CYTOMEGALOVIRUS COLITIS IS ASSOCIATED WITH POOR LONG-TERM OUTCOMES IN ADALIMUMAB THERAPY IN KOREAN PATIENTS WITH ULCERATIVE COLITIS: A HOSPITAL-BASED COHORT STUDY (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Eun Hye Oh
Background: Studies regarding long-term outcomes of adalimumab treatment in non-Caucasian patients with ulcerative colitis (UC) are still lacking. ... More...

P049 - HYPERCALCEMIA DUE TO ISOLATED ELEVATION OF 1,25-DIHYDROXYVITAMIN D IN A PATIENT WITH CROHN’S DISEASE: CASE REPORT AND REVIEW OF LITERATURE (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Zubair Khan
Introduction: Hypercalcemia has been described in patients with many granulomatous diseases. Elevated serum calcium levels in the setting of granul... More...

P050 - IBD CALL CENTER WORKFLOW CHANGES: IMPROVING PATIENT EXPERIENCE AND REDUCING ADMINISTRATIVE BURDEN (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Mark Mattar
Introduction: Due to the complexity of diagnosis and treatment of Inflammatory bowel disease (IBD), providers observe a large volume of patient inq... More...

P051 - IBD PATIENT COMPLIANCE WITH MOBILE AND WEARABLE TECHNOLOGIES AS TOOLS TO ASSESS QUALITY OF LIFE, SLEEP QUALITY AND PAIN (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Olivia Yvellez
Inflammatory bowel disease (IBD) is a chronic condition characterized by periods of remission and relapses. Periodic surveys are used to monitor di... More...

P052 - IMMUNO-CHECKPOINT INHIBITOR INDUCED COLITIS IN A PATIENT WITH LUNG CANCER AND COLON METASTASIS TREATED WITH MESALAMINE: A CASE STUDY (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Gladis Shuttlesworth
Background: Immuno-checkpoint inhibitor (ICI) is becoming an integral part of advanced cancer treatment. ICI can cause adverse events in multiple o... More...

P053 - IMMUNO-CHECKPOINT INHIBITORS INDUCED COLITIS TREATED WITH MESALAMINE (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Hamzah Abu-Sbeih
Background: Immuno-checkpoint inhibitors (ICI) are becoming an integral part of advanced cancer treatment. ICI-induced colitis (ICI-C) is one of th... More...

P054 - IMPACT OF INFLAMMATORY BOWEL DISEASE ON PHYSICAL MOBILITY AND QUALITY OF LIFE: PHYSICIAN AND PATIENT PHYSICAL REHABILITATION PERSPECTIVES DIVERGE (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Jessica Elia
Introduction: Inflammatory Bowel Diseases (IBD) are known to be associated with intra- and extra-intestinal symptoms such as pelvic floor dysfuncti... More...

P055 - IMPACT OF NEW BIOLOGIC AGENT APPROVAL FOR ULCERATIVE COLITIS ON TUMOR NECROSIS FACTOR INHIBITOR (TNF) PRESCRIBING: RESULTS FROM A NATIONAL PATIENT CHART AUDIT (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Sunandra Kane
Background: TNF-inhibitor(TNF) therapy was approved for use in moderately active ulcerative colitis (UC) in 2005. We were interested in studying to... More...

P056 - IMPLEMENTING MASS CYTOMETRY AS A TOOL FOR INFLAMMATORY BOWEL DISEASE RESEARCH (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Christopher Tyler
BACKGROUND An expanding range of therapeutics have been approved or are under development for IBD. However, objective readouts of treatment efficac... More...

P057 - IMPROVED QUALITY OF CARE AND QUALITY OF LIFE FOR IBD PATIENTS USING MOBILE BASED REMOTE MONITORING PLATFORM: A RANDOMIZED CONTROL TRIAL (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Ashish Atreja
Background: The recurrent and debilitating nature of Inflammatory Bowel Disease (IBD) makes affected patients ideal candidates to assess the therap... More...

P058 - INCREASES IN HEMOGLOBIN ARE ASSOCIATED WITH A DECREASED RISK FOR COLORECTAL CANCER IN VETERAN’S AFFAIRS INFLAMMATORY BOWEL DISEASE PATIENTS (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Katrina Herbst
Introduction/Background: Colorectal cancer (CRC) has long been associated with inflammatory bowel disease (IBD), thought to be due to chronic mucos... More...

P059 - INDOLEAMINE 2,3-DIOXYGENASE 1 EXPRESSION PROMOTES EPITHELIAL SECRETORY CELL DIFFERENTIATION VIA ARYL HYDROCARBON RECEPTOR (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): David Alvarado
Background: In mouse models of IBD, the tryptophan metabolizing enzyme indoleamine 2,3-dioxygenase 1 (IDO1) has been shown to limit disease severit... More...

P060 - INFLAMMATION-ASSOCIATED COLONIC LYMPHATIC ARCHITECTURE DISRUPTION IS AMELIORATED BY IRISIN A CHRONIC RODENT MODEL OF IBD (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Anand Narayanan
Background: The lymphatics are the main transport of lymph (containing fluid, macromolecules, and immunological components such as cells and cytoki... More...

P061 - INFLAMMATORY BOWEL DISEASE SEVERITY INFLUENCES VITAMIN D MONITORING (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Marie Borum
It has been suggested that vitamin D has a role in the pathogenesis and regulation of inflammatory bowel disease (IBD). However, physicians inconsi... More...

P062 - INTEGRIN ß7 DEFICIENCY RESULTS IN PAUCITY OF TERTIARY LYMPHOID TISSUES AND DECREASED LAMINA PROPRIA IGA+ B CELLS LEADING TO MICROBIOME DYSBIOSIS AND WORSE INFLAMMATION IN A MODEL OF CROHN’S-LIKE ILEITIS (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Joshua Boyer
Background: Integrin α4β7 expression on lymphocytes promotes their localization to the gut. A monoclonal antibody against these integrin... More...

P063 - INTERACTIONS OF GENETIC AND ENVIRONMENTAL FACTORS TRIGGER UNIQUE PPAR-GAMMA SIGNATURE IN PANETH CELLS IN CROHN'S DISEASE SUBJECTS AND RELEVANT MOUSE MODELS (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Ta-Chiang Liu
Background: Crohn's disease (CD) pathogenicity involves interplay of genetic and environmental factors (G+E). CD subjects and mice harboring AT... More...

P064 - INTERFERON-GAMMA INDUCED VASCULAR IMPAIRMENT CONTRIBUTES TO THE PATHOGENESIS OF INFLAMMATORY BOWEL DISEASES (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Victoria Langer
Background: Inflammatory Bowel Diseases (IBD) are characterized by upregulation of Interferon-gamma (IFN-γ). Recently we showed that IFN-&gam... More...

P065 - INTERNISTS’ PRACTICE AND PERCEPTIONS OF RESPONSIBILITY OF IBD-RELATED HEALTH MAINTENANCE (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Muhammad Hammami
Health maintenance (HM) of patients with IBD is multifactorial and of well-established importance. However, the extent that it is practiced and whe... More...

P066 - INTESTINAL EPITHELIAL MICROVILLI ARE ABNORMAL IN CROHN'S DISEASE (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Kelli VanDussen
Background and Aims: Crohn’s disease (CD) presents as chronic and often progressive intestinal inflammation, but the contributing pathogenic ... More...

P067 - INVESTIGATION OF THE PRESENCE OF MYCOBACTERIUM AVIUM SSP. PARATUBERCULOSIS IN CHILDREN WITH CROHN DISEASE USING QUANTITATIVE DNA SEQUENCE-BASED APPROACHES (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Casey E Hofstaedter
Background: Mycobacterium avium ssp. paratuberculosis (MAP) has been suspected to play a role in Crohn disease (CD) pathogenesis. Prior studies of ... More...

P068 - LIPID PHOSPHATE PHOSPHATASE-3 (LPP3) DEFICIENCY INTENSIFIES INTESTINAL INFLAMMATION IN THE DSS MODEL OF ULCERATIVE COLITIS: ROLES OF LYSOPHOSPHATIDIC ACID AND LYMPHATIC/VASCULAR NETWORKS IN INFLAMMATORY GUT INJURY? (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Moheb Boktor
Inflammatory bowel diseases (IBD), including Crohn's disease and ulcerative colitis (UC), affect more than 1 million people in the United State... More...

P069 - LOW FAT DIET IMPROVES QUALITY OF LIFE AND CHANGES THE MICROBIOME IN A CATERED, CROSS-OVER DESIGN INTERVENTION OF UC PATIENTS WITH QUIESCENT DISEASE: RESULTS OF A PILOT STUDY (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Matthew Philips
A diet high in animal meat and fat has been linked to an increased risk for ulcerative colitis (UC) and high meat intake increases the likelihood o... More...

P070 - MACROPHAGE-EXPRESSED ERBB4 PLAYS A PROTECTIVE ROLE IN THE ONSET AND RESOLUTION OF EXPERIMENTAL COLITIS (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Michael Schumacher
Background: Pro-inflammatory macrophages (Mø) are crucial for onset of intestinal inflammation, and defects that enable persistence of these cells ... More...

P071 - MECHANISM OF MMP-9 ACTIVATION OF MYOSIN LIGHT CHAIN KINASE (MLCK) MEDIATED DISRUPTION OF INTESTINAL TIGHT JUNCTION BARRIER (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Rana Al-Sadi
Background: Matrix Metalloproteinases 9 (MMP-9) has been implicated to have a key pathogenic factor in inflammatory bowel disease (IBD). MMP-9 is e... More...

P072 - MESENCHYMAL STEM CELLS AMELIORATE DSS-INDUCED CHRONIC COLITIS IN MICE BY INDUCING PHENOTYPIC CHANGES OF DENDRITIC CELLS. (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Hyun-Soo Kim
Background/Aim: Mesenchymal stem cells (MSCs), which are an emerging cell therapeutic for inflammatory bowel disease (IBD), have demonstrated immun... More...

P073 - MESENCHYMAL STEM/STROMAL CELLS REGULATE GUT INFLAMMATION AND INFECTION VIA IL-33 PRODUCTION (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Tanel Mahlakoiv
Interleukin (IL-)33 is a cytokine that possesses dichotomous functions in the gut. Whereas various cell types have been reported to produce IL-33, ... More...

P074 - MICROBIAL COMPOSITION IS EFFECTIVELY IMPROVED BY COMBINATION THERAPY WITH FECAL MICROBIAL TRANSPLANTATION AND MULTIPLE ANTIBIOTICS FOR ULCERATIVE COLITIS (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Dai Ishikawa
Background and Aims: Fecal microbiota transplantation (FMT) is an effective treatment for recurrent Clostridium difficile infection. To provide eff... More...

P075 - MICROBIAL INDUCTION OF TL1A LINKS PROTECTIVE AND PATHOGENIC ROLES FOR GROUP 3 INNATE LYMPHOID CELLS IN COLITIS (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Randy Longman
Background: Inflammatory bowel disease (IBD) results from a dysregulated interaction between the microbiota and a genetically susceptibe host. Poly... More...

P076 - MICRORNA SAFEGUARDING THE INFLAMMATORY COLON STEM CELL NICHE (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Xiling Shen
BACKGROUND: Inflammation triggers stem cell proliferation to repair the tissue damage, while abnormal gene expression can transform temporary hyper... More...

P077 - mTOR-MEDIATED SUPPRESSION OF AUTOPHAGY ACTIVITY IN CX3CR1+ MONONUCLEAR PHAGOCYTES CONTRIBUTES TO INTESTINAL FIBROSIS (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Ramkumar Mathur ; Xinjun Zhu
Intestinal fibrosis is a pathological consequence of excessive myofibroblast proliferation and collagen deposition, frequently seen in Crohn’... More...

P078 - MUCOSAL STEM CELL HETEROGENEITY IN PEDIATRIC CROHN’S DISEASE (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Wa Xian
Background: Crohn’s is an aggressive inflammatory bowel disease driven by interactions of unknown relative significance between the immune sy... More...

P079 - NEONATAL SUPPLEMENTATION OF A LACTOBACILLUS RHAMNOSUS GG (LGG)-DERIVED PROTEIN, P40, PROMOTES INTESTINAL DEVELOPMENT AND PREVENTS COLITIS IN ADULTHOOD (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Fang Yan
Background: p40 transactivates EGF receptor in intestinal epithelial cells, leading to protection of intestinal epithelial cells under the inflamma... More...

P080 - NEUTROPHIL EXTRACELLULAR TRAPS DEFICIENCY AGGRAVATES CHRONIC COLITIS (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Emilie Viennois
Neutrophils can release their DNA as neutrophil extracellular traps (NETs) via a programmed cell death known as NETosis; this process is dependent ... More...

P081 - NEUTROPHILIC PUSTULOSIS OF ULCERATIVE COLITIS: A SPECTRUM OF EXTRAINTESTINAL DISEASE (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Garrett Diltz
BACKGROUND: The pustular eruption of ulcerative colitis, also known as neutrophilic pustulosis, is a poorly defined, yet well-described extraintest... More...

P082 - OCULAR EVALUATIONS IN INFLAMMATORY BOWEL DISEASE: STEROID USE AND PATIENT ETHNICITY INFLUENCE REFERRAL RATES (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Marie Borum
Approximately 4-10% of individuals with inflammatory bowel disease (IBD) will have ocular manifestations. In addition, steroid use is associated wi... More...

P083 - OPIOID DEPENDENCE IS ON THE RISE AMONG IBD HOSPITALIZATIONS (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Shirley Cohen-Mekelburg
Introduction. Opioid abuse has reached epidemic proportions with over 12 million reporting a history of opioid misuse. Patients with inflammatory b... More...

P084 - ORAL DELIVERY OF NANOPARTICLES LOADED WITH GINGER ACTIVE COMPOUND, 6-SHOGAOL, ATTENUATES ULCERATIVE COLITIS AND PROMOTES WOUND HEALING IN A MURINE MODEL OF ULCERATIVE COLITIS (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Mingzhen Zhang
Background and Aims: Oral drug delivery is the most attractive pathway for ulcerative colitis (UC) therapy, since it has many advantages. However, ... More...

P085 - ORAL HEALTH STATUS OF ULCERATIVE COLITIS PATIENTS: A COMPARATIVE STUDY (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Delfin Lovelina Francis
Introduction: Inflammatory bowel disease (IBD) is a complex civilization disease and has a prevalence of upto 0.2% in the Asian countries. The dise... More...

P086 - OVER 30% OF SYMPTOMATIC FLARES IN INFLAMMATORY BOWEL DISEASE PATIENTS ARE ASSOCIATED WITH DETECTABLE GASTROINTESTINAL INFECTIOUS AGENTS BY THE BIOFIRE GI PCR PANEL STOOL TEST (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Peter Higgins
Background/Aims: GI infections (e.g. C. difficile and CMV) have been shown to worsen inflammatory bowel disease (IBD) activity and result in increa... More...

P087 - PATIENT INFLUENCE ON CHOICE OF BIOLOGIC TREATMENTS: A NATIONAL PATIENT CHART AUDIT (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Sunandra Kane
Background: Data are emerging about the role of patient input on decision making for treatment of IBD. There are now multiple options for biologics... More...

P088 - PERCEPTIONS AND USE OF USTEKINUMAB IN CROHN’S DISEASE: RESULTS FROM A NATIONAL PATIENT CHART AUDIT (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Sunandra Kane
Background: The treatment of Crohn’s disease has expanded with the development of biologics with different mechanisms of action. Ustekinumab,... More...

P089 - PERCEPTIONS REGARDING USE OF ANTI-TUMOR NECROSIS FACTOR TREATMENTS FOR WOMEN OF CHILDBEARING AGE AMONG HEALTHCARE PROFESSIONALS (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Anita Afzali
Background: For women with chronic inflammatory diseases, diagnosis and treatment initiation often overlap with peak reproductive years. High disea... More...

P090 - PHYSICAL ACTIVITY IS INFREQUENTLY ASSESSED IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Marie Borum
Background: Studies have shown that physical activity has therapeutic effects on inflammatory bowel disease (IBD) by reducing disease activity, imp... More...

P091 - PHYSICIANS INCONSISTENTLY MONITOR VITAMIN D IN INFLAMMATORY BOWEL DISEASE PATIENTS: GENDER AND ETHNICITY MAY PLAY A ROLE (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Marie Borum
Vitamin D may have a role in immune regulation and be associated with inflammatory bowel disease (IBD) expression. IBD patients are more likely to ... More...

P092 - PHYSIOLOGIC HYPOXIA AND LIPID PEROXIDATION PRODUCTS MODULATE GRANULOCYTE-MACROPHAGE COLONY STIMULATING FACTOR-DEPENDENT NEUTROPHIL BACTERIAL KILLING IN PEDIATRIC CROHN’S DISEASE (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Adam Price
Background. Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) enhances neutrophil regulation of gut bacteria. Crohn’s Disease (CD) pa... More...

P093 - PREDICTORS OF ANTIDEPRESSANT USE IN INFLAMMATORY BOWEL DISEASE IN A LARGE, RETROSPECTIVE HOSPITAL DATABASE (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Manasi Agrawal
Background Depression occurs in up to 21% of IBD patients and is associated with increased healthcare costs. Antidepressants (AD), used by nearly 2... More...

P094 - PROINFLAMMATORY RESPONSES OF THE INTESTINAL EPITHELIUM ARE PREDOMINANTLY FACILITATED BY STEM CELLS (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Michal Mokry
Background: A disturbed balance between reactivity and tolerance of the intestinal epithelium (IE) to bacterial compounds is one of the key contrib... More...

P095 - PSYCHOLOGICAL DISTRESS IN PATIENTS WITH CROHN'S DISEASE: A CROSS-SECTIONAL STUDY USING THE BRIEF SYMPTOM INVENTORY INSTRUMENT (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Shmuel Odes
Background: Crohn's disease (CD) patients all experience psychological distress, but its characteristics are incompletely understood. We report... More...

P096 - RADIATION AND IDO1-SELECTIVE INHIBITOR EPACADOSTAT EXHIBIT THERAPEUTIC SYNERGY IN COLITIS ASSOCIATED CANCER (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Baosheng Chen
BACKGROUND: We have previously demonstrated that gene deletion of the immunosuppressive enzyme IDO1 (indoleamine-2,3-dioxygenase 1) reduces but doe... More...

P097 - REGULATION OF PANETH CELL LINEAGES FOR REGIONAL IMMUNE SPECIALIZATION TO CONTROL COMORBIDITY OF C. DIFFICILE INFECTION WITH IBD (Room Poster Hall)

19 Jan 18
5:30 PM - 7:00 PM

Tracks: Clinical and Research Challenges

Speaker(s): Xiaonan Han
Background: Hormone-like cytokines control C. difficile infection and counteract IBD. Apart from secreting bactericidal products, Paneth or Paneth-... More...
Page 1 of 2