Crohn’s & Colitis Congress™

Sessions Speakers Exhibitors Floor Plan Buzz

P209 - EPIDEMIOLOGY OF NON-MELANOMA SKIN CANCERS IN HOSPITALIZED PATIENTS OF INFLAMMATORY BOWEL DISEASE IN USA: INSIGHTS FROM NATIONAL INPATIENT SURVEY (Room Poster Hall)

Introduction: Non-melanoma skin cancer (NMSC) is among the most common malignancies in the United States. Patients with inflammatory bowel disease (IBD) may be at increased risk for NMSC due to the immunosuppressive medications, the underlying immune dysfunction, or both. Methods: We analyzed the National Inpatient Sample (NIS) database for all subjects with primary or secondary discharge diagnosis of IBD (Ulcerative Colitis & Crohn’s Disease) during the period from 2002-2014. NMSC were then identified in this cohort via ICD 9 codes. All analyses were performed with the use of SAS, version 9.4 (SAS Institute). Results: From 2002-2014, there were 22620 discharges of NMSC in IBD, constituting 0.70 % discharges of IBD. Out of these, 9097 discharges were identified in UC constituting 0.77% of discharges and 13523 were identified in CD constituting 0.65% of discharges. Most of the patients with NMSC were of age above 50 (90.2%), with the highest prevalence in age group 71-80 (27.7%). Most of the IBD patients with NMSC were males (54% Vs 42.3%, P=<0.001), insured by Medicare (65% Vs 36.9%, P=<0.001), were Caucasians (96.4% Vs 81.2%, P=<0.001), in Midwest and west (27.4% Vs 25.5% & 21.6% Vs 16.5%), admitted to urban teaching hospitals (57.2% Vs 50.6%, P=<0.001), being discharged to skilled nursing facilities (15.7% Vs 9.5%, P=<0.001), requiring home health care (17% Vs 11.3%), admitted electively (27% Vs 19.8%) than without NMSC. There was no significant difference in mortality in IBD patients with and without NMSC (1.61% Vs 1.53%, P=0.22). The trend analysis showed slowly rising trend of NMSC in patients with IBD from 2002 (0.32%) to 2014 (1.24%). Conclusions: The prevalence of NMSC in IBD cohort was lower than reported in previous studies, and there was a rising trend of NMSC over the years. With the rising trend there was no parallel rise in mortality, but the morbidity was found to be increased.