8.3 Comprehensive Stability Analysis of Concentrated Emulsions and Dispersions
(Room 234-236)
10 Apr 18
10:00 AM
-
10:30 AM
Tracks:
Session 8: Measuring & Testing, Session 8: Measuring & Testing I
Development of stable emulsions is critical for formulation chemists who desire to have a stable, well-dispersed product that can also exhibit a desired shelf-life and avoid destabilization phenomena that will inhibit transfers between storage vessels. New materials and regulations are leading chemists to develop new formulas to meet these criteria. Visual analysis of these emulsions can be time-consuming and objective causing extensive project times and qualitative results, and other optical techniques involve disturbing or diluting the samples.
We present here a technique based on Multiple Light Scattering (MLS) to fulfill this purpose. Destabilization phenomena such as sedimentation, creaming, clarification and flocculation can be identified and quantified much fast than standard visual analysis. Such data can accelerate project timelines and provide critical data in order to optimize a formulation. It has proven to be a useful technique to characterize the dispersion state of colloidal samples and the mean diameter of particles in concentrated dispersions. Where other optical techniques ask a very high dilution and risk to denature the sample, this technique has the advantage to analyze in one click, without sample preparation or dilution, concentrated suspensions.