2015 AACC

Meet-the-Expert: From Gene Discovery to Novel Therapeutics for Prevention of Atherosclerosis-62001 (Room Georgia World Congress Center - B218)

27 Jul 15
10:30 AM - 11:30 AM

Tracks: Cardiovascular Disease, Genetics and Genomics Disorders, Lipids/Lipoproteins, Neurological Diseases

Speaker(s): Helen Hobbs, UT Southwestern Medical Center;

Moderator(s): Amy Saenger, Roche Diagnostics Corp.

After this session, participants will be able to: 1) explain how genetic information informs investigation of physiologic mechanisms of disease; 2) explain the role of loss-of-function alleles in disease mechanisms; and 3) explain how therapeutic reduction of PCSK9 affects LDL-cholesterol metabolism in the liver and reduces risk for heart disease.