Interference is a substance present in a patient specimen that can alter the correct value of the result by interfering with antibody binding, or that can increase or decrease assay signal by bridging, steric hindrance, or autoantibody mechanisms. Erroneous results can impact patient care, and can lead to unnecessary invasive, diagnostic or therapeutic procedures, or failure to treat a patient with a false negative test result. There is a CLINICAL NEED for a simple, inexpensive, automatable and effective solution to mitigate sample specific interferences.