This panel has been organized jointly by IEEE PES CFWG, NERC, North American Synchrophasor Initiative (NASPI) and US electric utilities and ISOs. Maintaining reliable and resilient operation of the bulk power system are fundamental aspects of grid operation, and focus on ensuring the system can withstand sudden disturbances or unanticipated failures of system elements such that instability, uncontrolled separation or cascading failures will not occur. Synchronized measurement technologies such as synchrophasor data from PMUs unlock the capability for improved real-time monitoring and control room solutions, as well as improved analysis of power system behavior in the planning horizon. Analyses of historical blackouts show that system operators could have mitigated and lessened the extent of outages had they had access to real-time data and software tools to identify an impending crisis. This panel will cover industry experience, perspectives and lessons learned with the use PMUs from three US Interconnections - WECC, Eastern Interconnection, and ERCOT.