Wire and cables play a crucial role in the performance of communications systems on almost all military hardware and weapon systems. Proper design of copper and fiber optic cables ensures that there are no malfunctions of these systems. To protect the cables against environmental and hazardous field conditions, cables are insulated with polymers and enclosed in metal or polymer jackets. Insulation and jacket slows down the signal transmission and introduce errors. Selection of right insulation material minimize reduction of signal speed (goal is for the signal to travel at the speed of light). Because multiple cables are used in most systems the performance suffers due to characteristics such as crosstalk, impedance, coupling, etc. The cable design must address these characteristics to ensure proper systems performance. Many cable problems are also caused due to wrong installation techniques. A sharp bend in cable crush the insulation resulting in changes in impedance and/or attenuation. The goal of Wire and Cable Knowledge tutorial is to educate DoD engineers and technicians about the design features and how they impact the performances. This knowledge is helpful in the selection of right cable, proper installation techniques and trouble shooting. The ultimate goal is to reduce downtime of communications and weapons systems. Over 80% of all systems performances are due to cable related issues.